There are 8 ways to get from Jacksonville to Alabama by plane, bus, train, or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly one-way from Jacksonville to Birmingham starting at $109. Bundle your Southwest Airlines® flight with a hotel or rental car booking and find even more savings.

Find flights to Alabama from $55. Fly from Jacksonville on Frontier, Southwest, American Airlines and more. Search for Alabama flights on KAYAK now to find the best deal.

The total driving distance from Jacksonville, FL to Alabama is 421 miles or 678 kilometers. Your trip begins in Jacksonville, Florida. It ends in the state of Alabama.

From Jacksonville, you can connect to Birmingham via Birmingham Intl. Airport (BHM), Gadsden, AL (GAD-Northeast Alabama Regional) and Anniston, AL (ANB-Anniston Municipal). It’s wise to check which airport is more convenient for you before you make a decision.

Jacksonville and Mobile are 5 hours 58 mins far apart, if you drive non-stop . This is the fastest route from Jacksonville, FL to Mobile, AL. The halfway point is Chattahoochee, FL. Please note the time difference between Jacksonville, FL and Mobile, AL is 1 hour.

Jacksonville and Birmingham are 7 hours 15 mins far apart, if you drive non-stop . This is the fastest route from Jacksonville, FL to Birmingham, AL. The halfway point is Sasser, GA. Please note the time difference between Jacksonville, FL and Birmingham, AL is 1 hour.

Cheap Flights from Jacksonville (JAX) to Huntsville (HSV) start at $175 for one-way and $350 for round trip. Earn your airline miles on top of our rewards!

Find airfare and ticket deals for cheap flights from Jacksonville to Alabama. Search flight deals from various travel partners with one click at $50.

Greyhound operates up to 3 trips daily from Jacksonville to Birmingham. You can find the schedule by entering your departure date in the search box above.