Lecithin–cholesterol acyltransferase (LCAT, also called phosphatidylcholine–sterol O-acyltransferase) is an enzyme found in many animals, including humans. It converts free cholesterol into cholesteryl ester, a more hydrophobic form of cholesterol.

Definition of LCAT in Military and Government. What does LCAT stand for?

Lecithin cholesterol acyltransferase catalyzes the formation of cholesterol esters in lipoproteins. Symptoms of the familial form include visual impairment caused by diffuse corneal opacities, target cell hemolytic anemia, and kidney failure.

Beta-LCAT activity helps attach cholesterol to other lipoproteins called very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL). More than 70 mutations in the gene have been identified in people with complete LCAT deficiency, a disorder that primarily causes corneal clouding and kidney problems.

Dec 13, 2023 · Lecithin cholesterol acyltransferase (LCAT) deficiency is a genetic disorder that affects the body’s ability to process cholesterol. It is characterized by cloudiness of the clear front surface of the eye (corneal opacities), a shortage of red …

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Jul 24, 2018 · Lecithin:cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma.

Lecithin cholesterol acyltransferase (LCAT) is a glycoprotein that has both a phospholipase A2 and an acyltransferase action. It is essential for the normal maturation, interconversion and rearrangements of all lipoprotein classes and is involved in reverse cholesterol transport.

Jul 13, 2021 · LCAT (lecithin-cholesterol acyltransferase) deficiency is characterized by two distinct phenotypes, familial LCAT deficiency (FLD) and Fish Eye disease (FED). This is the first systematic review evaluating the ethnic distribution of LCAT deficiency, with particular emphasis on Latin America and the discussion of three Mexican-Mestizo probands.

Mar 1, 2022 · Lecithin: cholesterol acyltransferase (LCAT) is the only enzyme in plasma which is able to esterify cholesterol and boost cholesterol esterify with phospholipid-derived acyl chains.