Jan 16, 2025 · Latest news New Insights Into Why Huntington’s Disease Has Delayed Onset. A highly-anticipated scientific paper has landed! This new work challenges current theories in Huntington’s disease research, uncovering how runaway CAG repeats erode cell identity in certain types of brain cells, leading to their death.

Dec 10, 2024 · Latest news Beta-blockers associated with delayed onset and decreased progression of Huntington’s disease. A well-studied, widely used class of drugs for heart health may have benefits for Huntington’s disease.

3 days ago · Glossary; Total Functional Capacity A standardized rating scale for function in HD, used to assess capacity to work, handle finances, perform domestic chores and self-care tasks ; NfL biomarker of brain health ; huntingtin protein The protein produced by the HD gene.; clinical trial Very carefully planned experiments designed to answer specific questions about how a drug affects human beings

Jan 18, 2011 · HDBuzz is now live! Your source for Huntington’s disease research news, in plain language, written by scientists, for the global HD community.

Self-determination on the HD journey: the role of Advanced Care Planning. Advanced Care Planning is a tool that can allow people living with Huntington’s disease to compassionately engage with loved ones about their future care, taking thoughtful steps at their own pace while they’re able, to ensure their wishes are met.

May 1, 2024 · HDBuzz strives to be an honest and neutral source of information that Huntington’s disease (HD) families can turn to for trusted, unbiased reporting on research and clinical trial news. We’re honored to have become a global resource for the HD community over the years (14!) and we look forward to building upon the original mission of …

Jan 20, 2025 · Glossary; blood-brain barrier A natural barrier, made from reinforcements to blood vessels, that prevents many chemicals from getting into the brain from the bloodstream ; CAG repeat The stretch of DNA at the beginning of the HD gene, which contains the sequence CAG repeated many times, and is abnormally long in people who will develop HD ; aggregate Lumps of protein that form inside cells in ...

Nov 1, 2012 · Welcome to HDBuzz! This special page is for people who are new to Huntington’s disease, or new to the world of HD research. Reading the articles linked here will help you pick up the basics of what Huntington’s disease is, and get up to speed with some of the most promising things scientists are doing to come up with effective treatments for HD.

Jan 13, 2025 · Glossary; ASOs A type of gene silencing treatment in which specially designed DNA molecules are used to switch off a gene ; neurodegenerative A disease caused by progressive malfunctioning and death of brain cells (neurons) ; transcription the first step in making a protein from the recipe stored in a gene. Transcription means making a working copy of the gene from RNA, a chemical messenger ...

Jan 2, 2025 · As we wave goodbye to 2024, the HDBuzz team reflects on a year marked by significant progress, challenges, and hope. From breakthroughs at the lab bench, advancements in drug development, and both road bumps and triumphs in clinical trials, we have gained new insights into the workings of Huntington’s disease (HD), and made great strides towards finding medicines which might slow or halt ...