The San Francisco 49ers appear to be inching closer toward a return for star running back Christian McCaffrey. Head coach ...

San Francisco 49ers head coach Kyle Shanahan provided a brief update on running back Christian McCaffrey ahead of Wednesday's ...

Injuries have plagued the San Francisco 49ers this season, and now another one looms. Brock Purdy and company could lose yet ...

The Niners are short-handed when it comes to playmakers on offense with Aiyuk out for the season and All-Pro running back ...

Brandon Aiyuk has been placed on injured reserve, dealing a major blow to the 49ers as they navigate key injuries.

San Francisco 49ers head coach Kyle Shanahan provided a brief update on running back Christian McCaffrey ahead of Wednesday's ...

The San Francisco 49ers may feel compelled to act with wide receiver Brandon Aiyuk lost for the season, worsening their injury crunch. ESPN's Dan ...

Dallas Cowboys pass-rushing linebacker Micah Parsons knows how his struggling team can slay the San Francisco 49ers.

ESPN's Seth Walder suggested Los Angeles Rams superstar receiver Cooper Kubb as a hypothetical blockbuster trade candidate ...

San Francisco 49ers RB Christian McCaffrey is currently on pace to return for the second half of the regular season.

The San Francisco 49ers were already expected to be active as the trade deadline approached. However, the season-ending knee ...