Ubiquitylation is a reversible post-translational modification involved in a myriad of cellular functions. A superfamily of approximately 100 ubiquitin-specific proteases, called deubiquitylating ...
Amgen is planning to push its olpasiran candidate for reducing lipoprotein(a) into phase 3 as quickly as possible as it tries to catch up with rival programmes at Novartis. The US biotech has just ...
The C-terminal TPRs of IFT172 constitute a binding site for IFT-A subunits. (A) Schematic representation of Homo sapiens (Hs) IFT172 protein domain organization. β-propeller and TPR (tetratricopeptide ...
Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark Department for Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark Department of ...
Winged helix (wH) domains, also termed winged helix-turn-helix (wHTH) domains, are widespread in all kingdoms of life and have diverse roles. In the context of DNA binding and DNA modification sensing ...
In this example, the cartoon representation shows an efflux pump-mediated ciprofloxacin resistance in Gram-negative bacteria. The AMP permeabilizes the membrane so more antibiotic can enter the ...
Cancer warning on alcohol, opioid epidemic’s ‘fourth wave,’ bird flu, weight loss drugs, health care startups, kidney stones in kids, and more.