Myopia, a leading cause of visual impairment globally, can progress to serious complications like retinal and choroidal degeneration. While atropine is commonly used to manage childhood myopia, its ...

‘This means they block muscarinic acetylcholine receptors, including those that stimulate sweat glands.’ When you don’t sweat, your body can't efficiently cool itself down through evaporation, an ...

‘This means they block muscarinic acetylcholine receptors, including those that stimulate sweat glands.’ ...

About NBI-1117568 NBI-1117568 is the first and only investigational oral muscarinic M4 selective orthosteric agonist in clinical development for the treatment of schizophrenia. There are five ...

The BMS drug treats schizophrenia by blocking muscarinic cholinergic receptors. There are five types of muscarinic receptors found in the brain and some peripheral tissues.

Xanomeline stimulates two key receptors found on brain cells that interact with acetylcholine: muscarinic acetylcholine receptors 1 and 4 (M1 and M4).

Cobenfy works by stimulating a pair of muscarinic receptors in the brain, that, in turn, control the release of acetylcholine.

More than 60% of complement inhibitor–naive patients with acetylcholine receptor–positive generalized myasthenia gravis (MG) in diverse clinical populations had a clinically meaningful ...

The company found a cognitive benefit with a compound called xanomeline, which focused on the M1 muscarinic acetylcholine receptors.

Bionomics is advancing its lead drug candidate, BNC210, an oral, proprietary, selective negative allosteric modulator of the α7 nicotinic acetylcholine receptor, for the acute treatment of Social ...