Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting ...

When GTP on Gα is hydrolyzed, the inactive Gαβγ heterotrimer re-associates for a new cycle of activation by the GPCR (Fig. 1). The GTP hydrolysis is strongly stimulated by a group of GAP (GTPase ...

Although metformin has been the go-to medication to manage type 2 diabetes for more than 60 years, researchers still do not ...

The amount of each of the more than a thousand different glycoproteins in your blood varies widely, with the 10 most abundant ...

The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting ...

At 12 weeks, patients treated with ENV-101 showed statistically significant increases in lung volume compared with those receiving placebo.

They’ve shown how a single signaling pathway can switch feathers back to a more primitive state—and how that switch can flip back again.

Decabromodiphenyl ethane (DBDPE), an emerging ubiquitous contaminant, enters the food chain through crop bioaccumulation, threatening food safety. This study investigated the bioaccumulation, toxicity ...

How disturbed signaling pathways could promote epileptic seizures Date: April 16, 2025 Source: Universitatsklinikum Bonn Summary: Focal cortical dysplasia (FCD) type 2 is a congenital malformation ...

Overall, the study provides comprehensive functional evidence for the role of the Shh pathway in mediating feather development in chickens, supporting the idea that modified Shh signaling has ...