A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...

Discover the potential of macrocycles in drug discovery: flexible, cell-permeable molecules targeting undruggable proteins.

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical ...

Therefore, there is the prospect of developing structure-based knowledge of ... where toxicity concerns could mean that a drug should only target one of a group of closely related proteins ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the ...

But not all target proteins were receptive to this method, called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not be ...

Bacterial cells differ fundamentally in their structure from animal ... molecules so special is that they target IspD, a protein that is not addressed by any drug currently on the market.

A couple of University of Nebraska professors have launched a startup company with the goal of bringing to market an ...

with a Buy rating and $50 price target Structure aims to expand the reach of metabolic treatments across the large, heterogeneous obesity landscape by way of its drug discovery platform of oral ...

"Since trypanosomes carry a special RNA cap structure, we were also interested ... lab who contributed to the publication. A potential drug target and future studies Because it is essential ...