The A/E/F tricyclic system characteristic of C18-, C19-, and denudatine-type C20-diterpenoid alkaloids was constructed via a strategically designed polyene cyclization/Mannich cascade. The ...

Diterpene synthase plays an important role in the biosynthesis of novel diterpenoids with diverse biological activities. In this study, two uncommon diterpene synthases, AsSS and CvSS, were discovered ...