Inside the Internet Archive it is as quiet as any library. But the subterranean staff working room in its cavernous San Francisco headquarters feels more like a bunker, the nerve center of an ...

Our study, which used brain scans to determine participants’ brain age, suggests that poor sleep is linked to nearly three ...

San Francisco is the nation's leading tech-hub and a popular international tourist destination. The city offers visitors a unique blend of chilly summer fog, steep rolling hills and eclectic mix of ...

D.A. George Gascón glided into office on a wave of calls for criminal justice reform. But after a rocky first term, his ...

Tesla stock shot up nearly 12% in pre-market trade on Thursday, a day after it forecast surging car sales growth, reassuring ...

The San Francisco 49ers have a long list of players missing from their first Week 8 practice. Headlining that list are two of ...

Sign up below to get Mission Local’s free newsletter, a daily digest of news you won’t find elsewhere.

A man is suing Alaska Airlines after he says he bought a first-class seat for his dog but they were pressured to move to ...

Walmart has agreed to pay $7.5 million to settle a lawsuit filed by California officials that alleged the retail giant ...

The wide receiver position has taken a significant hit for the San Francisco 49ers. Brandon Aiyuk will miss the remainder of the season with a torn ACL and MCL.

The 49ers' Nick Bosa expects the Dallas Cowboys to attempt a more run-oriented approach when they visit Levi's Stadium ...

While serving in the U.S. Senate, Kamala Harris celebrated the Democrat primary victory of Philadelphia progressive ...