San Francisco 49ers head coach Kyle Shanahan provided a brief update on running back Christian McCaffrey ahead of Wednesday's ...

Brock Purdy has the chance to do something special as he looks to keep the injury-hit San Francisco 49ers alive in their pursuit of a Super Bowl; watch the 49ers take on the Dallas Cowboys in Sunday ...

The 49ers and Kyle Shanahan shared encouraging news involving their All-Pro wide receiver before facing the Dallas Cowboys.

Injuries have plagued the San Francisco 49ers this season, and now another one looms. Brock Purdy and company could lose yet ...

The Niners are short-handed when it comes to playmakers on offense with Aiyuk out for the season and All-Pro running back ...

San Francisco 49ers head coach Kyle Shanahan provided a brief update on running back Christian McCaffrey ahead of Wednesday's ...

The Dallas Cowboys are set to face off against a team on Sunday that is dealing with just as many injury issues as they have ...

The San Francisco 49ers may feel compelled to act with wide receiver Brandon Aiyuk lost for the season, worsening their injury crunch. ESPN's Dan ...

Dallas Cowboys pass-rushing linebacker Micah Parsons knows how his struggling team can slay the San Francisco 49ers.

ESPN's Seth Walder suggested Los Angeles Rams superstar receiver Cooper Kubb as a hypothetical blockbuster trade candidate ...

San Francisco 49ers RB Christian McCaffrey is currently on pace to return for the second half of the regular season.

The San Francisco 49ers were already expected to be active as the trade deadline approached. However, the season-ending knee ...