Of the 91 patients originally diagnosed with PMA, 20 subsequently developed upper motor neuron signs, which would qualify them as having ALS with lower motor neuron onset. Furthermore, upper motor ...

Multiple models have been proposed for the mechanism by which mutant superoxide dismutase 1 induces motor neuron death and amyotrophic lateral sclerosis ... degeneration of upper and lower ...

After suffering a brainstem stroke, Jean-Dominique Bauby only retained movement in his left eye. Remarkably, he was still able to write The Diving Bell and the Butterfly.

Correspondence to Leonard H van den Berg, Department of Neurology, G03.228, University Medical Center Utrecht, PO Box 85500, Utrecht 3508 GA, The Netherlands L.H.vandenBerg{at}umcutrecht.nl Objective ...

It is often difficult to identify signs of upper motor neuron lesion in the limbs of patients with amyotrophic lateral sclerosis, in whom there is neurogenic muscle wasting of varying severity. The ...

PrimeC, a fixed-dose combination of two FDA-approved drugs, ciprofloxacin and celecoxib, targets multiple ALS disease pathways such as motor neuron degeneration, inflammation, and RNA regulation.

Former AFC Leopards forward Ezekiel Otuoma passed away on Friday night, December 20, after a long battle with Motor Neuron Disease (MND ... The disease, also known as Amyotrophic Lateral Sclerosis ...

Despite the lower ALS risk, heart and metabolism problems are tied to faster disease progression and worse survival in the ...

mimicking ALS motor neuron responses. “Our approach provides a robust platform for studying ALS-specific cellular vulnerabilities and offers unprecedented opportunities for drug screening ...

ALS, also known as Lou Gehrig's disease, is the most common degenerative motor neuron disease in adults. It is characterized by a selective loss of motor neurons, resulting in progressive muscle ...

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is the most common degenerative motor neuron disease in adults. It is characterized by a selective loss of motor neurons ...

Amyotrophic lateral sclerosis (ALS) is a fast-progressing ... system to identify potential drugs to delay or prevent these motor neuron deaths. To automatize the analysis of these cells, the ...