Now, the researchers have learned more about what can control the traffic-controlling HTT.

University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease?

Both drugs are designed to switch on the SMN2 gene ... that is mutated in Huntington's. HTT provides instructions to make the huntingtin protein, which is misfolded in Huntington's disease ...

High dose and low dose AMT-130 demonstrated an 80% and 30% slowing of disease progression vs external control, respectively. The Food and Drug Administration has granted Breakthrough Therapy ...

A survey conducted in Canada examined the prevalence of perceived genetic discrimination against patients with Huntington disease. The respondents reported discrimination not only by insurance or ...

University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin ...

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease? They found that ...

How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease? They found that HTT is something like a traffic controller inside neurons, moving different cargo along neuronal ...