However, CSF markers showed early signs of neurodegeneration in the ... repeat expansion driving the neurodegeneration in Huntington’s disease,” Tabrizi said. “These findings are important ...

where those at risk of developing Huntington's disease are functioning normally despite having detectable measures of subtle, early neurodegeneration. Identifying these early markers of disease is ...

emerged decades before clinically diagnosable Huntington's disease. Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated NfL ...

CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease ... People who inherit the disease seem perfectly normal early in life.

where those at risk of developing Huntington's disease are functioning normally despite having detectable measures of subtle, early neurodegeneration. Identifying these early markers of disease is ...

The findings suggest that there is a treatment window, potentially decades before symptoms are present, where those at risk of developing Huntington’s disease are functioning normally despite having ...