Antibiotics are a double-edged sword—they should be as toxic as possible to pathogenic bacteria while being harmless to the ...

Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to ...

Proteins are the foundation of all life we currently know. With their virtually limitless diversity, they can perform a broad ...

Discover the potential of macrocycles in drug discovery: flexible, cell-permeable molecules targeting undruggable proteins.

Scientists develop DNA nanorobots capable of modifying artificial cells. Scientists at the University of Stuttgart have ...

Preclinical research findings from the University of North Carolina Lineberger Comprehensive Cancer Center have identified a ...

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells ...

The results of a phase 2 trial of MSD’s ROR1 inhibitor zilovertamab vedotin (zilo-V) back up the company's decision to push the antibody-drug conjugate (ADC) into a phase 3 programme. Presented ...

Jan. 13, 2025 — A new study found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. However, the findings also show ...

Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting ...

Researchers have used a groundbreaking geometric deep learning method, MaSIF, to design proteins that bind specifically to ...