Discover the potential of macrocycles in drug discovery: flexible, cell-permeable molecules targeting undruggable proteins.

Antibiotics are a double-edged sword—they should be as toxic as possible to pathogenic bacteria while being harmless to the ...

The starting point for all structure-based design work, whether ligand or protein based, is the choice of a suitable target. Antimicrobial-drug targets should be essential, have a unique function ...

The resulting images became the first known structure of a complete aGPCR ... are very different from each other, so you can target them with a drug that doesn't bind to other receptors and ...

Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to ...

with a Buy rating and $50 price target Structure aims to expand the reach of metabolic treatments across the large, heterogeneous obesity landscape by way of its drug discovery platform of oral ...

Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, ...

While challenges remain, AI is accelerating the process by enabling researchers to identify and design new drug candidates ...

Stifel initiated coverage of Structure Therapeutics (GPCR) with a Buy rating and $50 price target Structure aims to expand the reach of ...