eLife13d
Disentangling acute motor deficits and adaptive responses evoked by the loss of cerebellar output
Cerebellar patients exhibit various motor impairments, but the sequence of primary and compensatory processes leading to these deficits remains unclear. To investigate this, we reversibly blocked ...
BioSpace20d
Solid Biosciences Receives FDA Fast Track Designation for SGT-212 Dual Route of Administration Gene Therapy for Friedreich’s Ataxia
Only dual route gene transfer therapy in development to treat Friedreich’s ataxia with FDA ... precision MRI-guided device, followed by an intravenous (IV) infusion to increase therapeutic FXN levels ...
CBC.ca20d
P.E.I.'s first private MRI clinic set to open in Summerside this spring
to accommodate the clinic. Guy Boswall says the clinic plans to recruit from across Canada and will try not to encroach on the MRI staff at the Queen Elizabeth Hospital. (Wayne Thibodeau/CBC ...
eLife26d
Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques
This important study examined neuronal activity in the dentate nucleus of the cerebellum when monkeys performed a difficult perceptual decision-making task. The authors provide convincing evidence ...
ahajournals.org27d
Abstract 222: CHANTER Syndrome: A Rare Cause of Encephalopathy
An MRI demonstrated confluent areas of restricted diffusion in the bilateral cerebellar hemispheres ... memory impairment, and appendicular ataxia, which improved during his hospital stay. By the time ...
Frontiers28d
Effect of long-term transcutaneous auricular vagus nerve stimulation in multiple system atrophy-cerebellar subtype: a case report
Background: Multiple system atrophy-cerebellar subtype (MSA-C) is a predominance of cerebellar ataxia and autonomic failure ... Magnetic Resonance Imaging (MRI) of the cranium showed hot cross bun ...