The Hughes Fire near Castaic, California, has burned over 5,000 acres, prompting evacuations and school closures.

A rare Particularly Dangerous Situation warning has been issued for Southern California as a powerful and potentially damaging Santa Ana wind event​ is expected.

The Los Angeles haven’t spread in nearly a week, but the return of the Santa Ana winds to full strength could cause problems.

Just a few years after the ozone hole was detected via satellite, the industrialized nations of the world, meeting in Montreal in 1987, adopted what is known as the Montreal Protocol.

The Santa Anas are expected to be most powerful Monday night into Tuesday. Fire services across the region say they are ready.

A wind-driven wildfire charred dozens of acres in the sparsely developed northeastern reaches of San Diego County, damaging structures and forcing pre-dawn evacuations before crews could gain the upper hand on the flames Wednesday.

Santa Ana winds occur when air flows west from a region of high pressure over the dry Great Basin to lower pressure off the California coast, According to Accuweather. As that cool interior air flows over and through mountain passes, it accelerates, sinks and compresses.

After a weekend of reprieve allowing fire teams to continue making progress battling the deadly infernos burning in Los Angeles County, Southern California now faces another round of fire-fueling Santa Ana winds.

"A strong Santa Ana Wind event is expected to develop Monday and last through at least Tuesday," the National Weather Service said.

Meteorologists said there was a chance the winds would be as severe as those that fueled the Palisades and Eaton fires, but that different locations would likely be affected.

California Governor Gavin Newsom has deployed fire engines, water-dropping aircraft and hand crews across the region—to enable a rapid response if a new fire does break out, according to The Associated Press.