According to the American Cancer Society (2005), at least 30 different tumor suppressor genes have been identified, including those listed in Table 2. Many of these genes function to inhibit cell ...

Can tumor suppressor genes and proto-oncogenes provide clues ... will die of cancer in the United States in the year 2008. Table 1 shows the predicted distribution and percentages of these deaths ...

Identification of genes inactivated by promoter CpG methylation is a powerful approach to discover novel tumor suppressor candidates. PCDH10suppresses gastric cancer cell growth through cell ...

Their cells still behave normally, but every so often the gene's second copy mutates in somatic cells, leading to disease. In 1993, National Institutes of Health researchers successfully identified ...

Loss-of-function variants in genes encoding tumor suppressor proteins, such as those that mediate DNA repair and cell-cycle checkpoints, can also contribute to an unstable genome. A gene that ...