What was puzzling was why sickle cell anemia was so prevalent in some African populations. How could a "bad" gene-- the mutation that causes the sometimes lethal sickle cell disease -- also be ...

Can we predict that natural selection will weed out genetic disease over time? Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated ...

On this map, the distribution of sickle-cell anemia haplotypes among nations ... distribution shows the genetic advantages of this mutation.

Sickle cell anemia is the most common inherited blood disorder and affects roughly 100,000 people in the United States at a given time. It's caused by a mutation of the hemoglobin gene ...

Children with sickle cell disease, a chronic hemolytic anemia, present with a wide variety ... in the Americas and Europe. The causative mutation is the substitution of valine for glutamic acid ...