A new study supports the clinical utility of human nasal epithelial cultures as predictive biomarkers for cystic fibrosis CFTR modulator therapy.

Epithelial cells were seen primarily as passive defenders — barriers that absorb and secrete, but do not talk. That perception may now be outdated. Also read Breakthrough Nasal Spray Offers Hope ...

Jingjing Liu, a graduate student in Shulman’s group and study coauthor, determined that responding B cells were activated in a compartment of the nasal cavity called the nasal-associated lymphoid ...

A further barrier to nasal delivery is the existence of tight junctions between epithelial cells in the mucous membranes inside the nose, which can prevent the penetration of large molecules such as ...

Core Function #1: Procure, grow, and distribute well-differentiated primary human epithelial cells and organoids from CF and non-CF donors. If you are an established user of primary airway cells, to ...

We don’t know much about the regulation of endocytosis and cell-to-cell transport in the muco-ciliary epithelium of the upper respiratory tract. Viruses, on the other hand, know all about it. We use ...

Both are epithelial cells, a cell type that forms barriers such as skin and mucous membranes, and also lines organs and body cavities. After blasting some cells with lasers, Yu measured tiny ...

Interactions between alveolar epithelial cells and macrophages shape lung development ... Here, authors present apical-out nasal organoids using a biochemically defined hydrogel system, revealing ...

Dysregulation of the interaction between epithelial cells and the adaptive immune system ... have been found to be increased in nasal secretions and mucosal tissue of patients with CRS.