HDBuzz has ramped up to match the accelerating pace of Huntington’s disease research. April 2025 brought us insight on ...

The genetic mutation that causes Huntington's disease (HD)—a devastating brain ... Expansion of a CAG triplet repeat stretch within the Huntingtin gene results in a different (mutant) form ...

Huntington’s disease (HD) is caused by extra repeats of the DNA letters CAG within the genetic code of the huntingtin gene. We used to think that those CAG lengths were stable in most tissues, but we ...

What are the current treatments for Huntington’s disease? Currently ... The disease is an autosomal dominant condition with a disease-causing CAG repeat expansion in the first exon of the ...

The US Food and Drug Administration (FDA) has awarded breakthrough therapy designation to uniQure's AMT-130 for treating Huntington's disease, a rare neurodegenerative condition. This designation ...

One of the areas of the brain where these cells congregate is the ventricular zone, which is adjacent to the striatum, a region of the brain devastated by Huntington's disease. The idea that the ...

Northern Scotland has one of the highest rates of Huntington’s disease globally, according to new research from the University of Aberdeen. For the first time in 35 years, scientists have ...

The number of people living in the area who have the gene that causes the condition has been accurately counted for the first time in 35 years in research by the University of Aberdeen ...

The genetic mutation that causes Huntington's disease (HD)—a devastating brain ... Expansion of a CAG triplet repeat stretch within the Huntingtin gene results in a different (mutant) form ...