They were particularly drawn to features of T7 DNA polymerase—derived from the T7 bacteriophage that infects Escherichia coli—due to its ability to synthesize long stretches of DNA by binding and ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

Scientists have yet to identify a polymerase that can add bases to the 5' ends of DNA strands ... eukaryotic cells share many of the same basic features of replication; for instance, initiation ...

Major replication features in simpler organisms extend ... Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage. Molecular Biology of the Cell 18 4085 ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial DNA. Without it, the mitochondria cannot function normally and, as a result, fail to provide the ...