CRISPR–Cas12a has a low tolerance for base-pair mismatches ... Since we are developing in vivo medicines, our goal was to design editors that would eliminate even potential risks and edit ...

As an advocate for the needs of researchers working at the forefronts of genomic research, Integrated DNA Technologies (IDT) releases its latest CRISPR enzyme Alt-R® Cas12a (Cpf1) Ultra. Cas12a Ultra ...

The new tool, which is called CRISPR-Cas12a, can help researchers simultaneously assess the impact of multiple genetic changes involved in variety of immune system responses, the researchers say. “We ...