More information: Fabienne Benz et al, Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans, Cell Host & Microbe (2024). DOI: 10.1016/j.chom.2024.04.016 ...

Identify the optimal CRISPR plasmid backbone, design and insert the guide RNA (gRNA) into the plasmid, synthesize and insert repair templates with homology arms into plasmid, obtain final construct ...

(6) In bacteria, scientists modify either the plasmid or chromosomal DNA of the microbe. In complex microbial communities such as the gut microbiome, CRISPR-engineered bacteria have multiple ...

(6) In bacteria, scientists modify either the plasmid or chromosomal DNA of the microbe. In complex microbial communities such as the gut microbiome, CRISPR-engineered bacteria have multiple ...

Collaborating with CRISPR-Cas9 co-inventor Jennifer Doudna and Jill Banfield at UC Berkeley, Steven Jacobsen, a distinguished professor of molecular, cell and developmental biology at UCLA ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

The study, published in Nucleic Acids Research, introduces BLU-VIPR, a method that allows researchers to control the gene-editing tool CRISPR using light. This innovation could significantly ...