Differentiation of transient hyperammonemia of the newborn and urea cycle enzyme defects by clinical presentation. J Pediatr 107:712-719, 1985.

Conducted during his time at Washington University in St. Louis, the study found that these urea cycle defects lead to secondary impairment in the tricarboxylic acid (TCA) cycle, a key pathway for ...

Researchers at the Center for Cognition and Sociality reveal the presence of a functional urea cycle in the star-shaped cells of the Alzheimer’s Disease (AD) brain. Key results point to the role ...

New research explores the urea cycle’s strong connection to fatty liver disease Peer-Reviewed Publication Indiana University School of Medicine ...

Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease. Cell Metabolism, 2022; DOI: 10.1016/j.cmet.2022.05.011 ...

Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism. Cell Metabolism, 2024; DOI: 10.1016/j.cmet.2024.07.007 ...