The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...

Parkinson's disease affects the brain neurons, causing damage and also affects the movement, tremor and stiffness, but do you ...

Figure 1: Respiratory chain deficiency and analysis of mtDNA deletions in substantia nigra neurons. We then wished to determine the nature of the mtDNA defect within the individual neurons in the ...

Please provide your email address to receive an email when new articles are posted on . There is a need to look past dopaminergic therapy and target inflammation for disease modification. Chronic ...

Deep in the human brain, a very specific kind of cell dies during Parkinson’s disease. For the first time, researchers have sorted large numbers of human brain cells in the substantia nigra into 10 ...

About The Study: In this cross-sectional study of contact sports athletes with chronic traumatic encephalopathy (CTE), years of contact sports participation were associated with substantia nigra tau ...

The death of dopaminergic neurons in the substantia nigra is the defining feature of Parkinson’s disease, but not all neurons in the region suffer this fate. Why do some wither while others survive ...

Parkinson's disease is an illness that affects the part of your brain that controls how you move your body. It can come on so slowly that you don't even notice it at first. But over time, what starts ...

You check into a hotel and toss and turn all night, but your sleep improves the following night. Scientists at Nagoya University wanted to understand why this happens. Working with mice, they have ...