The development of the dorsal spinal cord, where sensory inputs like touch and pain are processed, is characterized by precise compartmentalization and organization. For these sensory processes to ...

Addition of BMP7 during neuronal differentiation further dorsalizes postmitotic population. (A) Timeline of dorsal differentiation from H120-NMPs, with BMP7 added during neuronal differentiation ...

When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals ...

The spinal cord formation begins around embryonic day 9 (e9) in mice. During development, the neural tube generates 11 types of neural progenitors along the dorsal ventral axis.

Amphix Bio, a company spun out from Stupp’s Northwestern laboratory, is helping navigate the FDA approval process and has received early feedback from the agency on the drug development program for ...

This new model, in contrast, recapitulates the development of all three sections of embryonic brain and spinal cord simultaneously—something that has not been achieved in previous models. While ...

One of the most formidable tasks for people who experience a spinal cord injury (SCI) is regaining control over their body movements. Such control allows them to hold a mug or use a computer, for ...

Cervical spinal stenosis refers to a narrowing of the spinal canal. If the canal narrows significantly, it can become too small for the spinal cord and nerve roots.

The development of the dorsal spinal cord, where sensory inputs like touch and pain are processed, is characterized by precise compartmentalization and organization.

Scientists discover ‘entirely unanticipated’ role of protein netrin1 in spinal cord development Known for its axon guidance properties, new research suggests protein is critical in guiding ...