Polygenic background bidirectionally modifies the penetrance of pathogenic variants in hypertrophic (HCM) and dilated (DCM) ...
Risk for ASD is strongly genetically influenced and reflects several types of genetic variation 1,2,3,4,5,6,7. Common polygenic variation, distributed across the genome, accounts for at least 20% of ...
Breakthroughs in genomics have begun to unravel the genetic architecture of schizophrenia risk, providing methods for quantifying schizophrenia polygenic risk based on common genetic variants. Our ...
The American Society for Reproductive Medicine published a report that concludes preimplantation genetic testing for ...
The Alzheimer's disease pathological cascade unfolds in the brain over decades, amidst a menagerie of cell types reacting to change. How, and when, does each cell type contribute to the process? A ...
Please provide your email address to receive an email when new articles are posted on . NEW ORLEANS — Causal artificial intelligence used to augment a polygenic risk score for CAD helped estimate how ...
Survey reveals nearly three-quarters of U.S. adults support using emerging technology to screen embryos during IVF for risk of developing certain health conditions or traits that arise from more than ...
Polygenic risk scores (PRS) combined with clinical factors improve POAG risk prediction, aiding in identifying high-risk patients. The study used OHTS data, showing low polygenic risk correlates with ...
Image: Polygenic risk scores for a disease for different people in a population. Each circle represents a person. Those with higher scores (red) are more likely to get the disease and those with lower ...
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