Antimuscarinics, which are a standard treatment for OAB, work by binding to muscarinic receptors in the bladder and inhibiting involuntary bladder contractions.

Muscarinic receptor antagonist: A class of drugs that inhibit the action of acetylcholine on muscarinic receptors in the bladder, thereby reducing involuntary contractions and discomfort.

The study shows it is possible to boost myelination by targeting human oligodendrocyte progenitor cells with solifenacin, an anti-muscarinic drug that currently is approved and marketed to treat ...

At the same time, this drug left alone the peripheral muscarinic receptors. When BMS reached a $14 billion deal to acquire Karuna last December, the schizophrenia drug was already under FDA review.