New understanding of a receptor key to allergic responses and anaphylaxis in conditions like asthma could offer a new ...

In mast cell activation syndrome, these cells become hyperresponsive, releasing their chemical arsenal inappropriately in response to harmless substances or even without any identifiable trigger.

More information: Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay., Cell (2024). DOI: 10.1016/j.cell.2024.07.014 ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Scratching an itchy rash really does make it worse, according to new research. But it can also provide defence against bacterial skin infections, say American scientists. New research, published in ...

Because mast cells in mice don’t possess Siglec-6 receptors, the researchers developed a model with human mast cells in their tissues. The mice were exposed to an allergen, and the nanotherapy ...

B, B cell; DC, dendritic cell. Created with BioRender.com. Credit: Nature (2023). DOI: 10.1038/s41586-023-06188-0 The function of mast cells, which are part of the immune system, is still a mystery.

Mast cells are hematopoietic cells residing in barrier tissues, e.g., epithelia of the gastrointestinal (GI) tract, lungs, and skin, best known for their roles in IgE-mediated allergies, affecting ...