Inhibikase Therapeutics said on Wednesday it would stop development of its experimental Parkinson's disease drug after it failed to improve patients' ability to carry out daily tasks such as eating ...

Levodopa is the most efficacious agent for the treatment of motor features of Parkinson's disease but its chronic use is associated with the development of motor complications. Mounting evidence ...

For decades, doctors have treated Parkinson's by giving patients levodopa, the inactive substance in the brain that once converted makes dopamine. "Levodopa is a replacement strategy. We all make ...

Problems with chemical messengers like dopamine were tied to posture issues in SMA in a mouse study, but levodopa therapy may ease symptoms.

Parkinson’s disease is a progressive neurodegenerative disorder that affects millions of people worldwide. In the United ...

Researchers uncovered new findings about involuntary muscle movements that come with long-term administration of Parkinson's drug levodopa. University of Arizona researchers have revealed new ...

Diet may also help your body handle Parkinson’s medications better. Research suggests that diet may play a role in boosting the efficacy of drugs like levodopa and in helping to manage side effects.

Ketamine disrupts abnormal brain activity, offering long-term relief for Parkinson’s dyskinesia in early clinical trials.

However, over a number of years, the brain of a Parkinson’s patient adapts to the levodopa treatment, and long term levodopa therapy can lead to dyskinesia, explained lead author Abhilasha ...

GOTHENBURG, SE / ACCESS Newswire / January 23, 2025 /IRLAB Therapeutics (STO:IRLAB-A)(FRA:6IRA) Gothenburg, Sweden, January ...

In fluctuating Parkinson's disease (PD) patients, treatment of PD using the catechol-O-methyl transferase inhibitor entacapone with carbidopa/levodopa improves quality of life and activities of ...

Over the years, the brain of a Parkinson's patient adapts to the levodopa treatment, which is why levodopa causes dyskinesia in the long term, said Abhilasha Vishwanath, the study's lead author ...