Small molecular inhibitors that interfere with the interactions between Bcl-2 members, for example between BCL-2 and BAX, have been shown to promote apoptosis. Perhaps the most advanced of these ...
Previous studies revealed a positive correlation between O-GlcNAcylation and tumor growth via the stabilization of target proteins, with O-GlcNAcylation transferase (OGT) being the only enzyme capable ...
Under normal conditions, cells that have undergone apoptosis end up condensed and ... cells or by professional phagocytes. Although the inhibition of blebbing does not interfere with ...
The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...
The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...
A recent study has shed new light on the role of fibro-adipogenic progenitors (FAPs) in muscle regeneration, fibrosis, and degeneration. These cells play a crucial part in tissue homeostasis, and ...
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