A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or ...

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The Huntington's mutation involves a stretch of DNA in the HTT gene in which a three-letter sequence of DNA, "CAG," is repeated at least 40 times, as opposed to the 15-35 repeats inherited by ...

Huntington's disease is a neurodegenerative disorder that is usually fatal about 15 to 20 years after a patient is diagnosed. It is known ... | Genetics And Genomics ...

Huntington’s disease symptoms are linked to expanding DNA repeats (CAG) that become toxic in brain cells over time The "ticking DNA clock" accelerates after 80 repeats, killing neurons within ...

The mutations that cause Huntington's involve a repeat of a three base pair sequence: CAG in the huntingtin gene. In Huntingon's patients, the CAG sequence is repeated forty or more times, instead of ...

has now revealed a possible molecular mechanism explaining how the DNA repeats are broken and then expanded in the Huntington's disease gene. Freudenreich and her research team report the results ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

New findings suggest Apolipoprotein B mRNA editing catalytic proteins are causing repeat expansions in the Huntington’s gene. Could targeting them offer a treatment? #huntingtonsdisease # ...

Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease ...

Previously reported data combined with these new findings “really point towards somatic CAG repeat expansion driving the neurodegeneration in Huntington’s disease,” Tabrizi said.