Systems biology of TGF-β signaling in normal and cancer cells We aim to understand the role of transforming growth factor-β (TGF-β) signaling in normal and cancer cells. TGF-β is a multi-functional ...

Discover how chronic oversleeping disrupts circadian rhythms, metabolism, and skin health, affecting overall wellbeing.

Other signaling molecules must move much farther ... Dopamine receptors bind dopamine, insulin receptors bind insulin, nerve growth factor receptors bind nerve growth factor, and so on.

Transforming growth factor-beta (TGF-β), a well-known morphogen ... of Sciences revealed the molecular mechanism of TGF-β ...

Here, authors reveal how cell stress reduces growth factor signaling, enriching polyunsaturated fatty acids in phospholipids and sensitizing membranes to oxidative damage. Lipid droplets (LDs ...

A group of scientists recently discovered that the hormone fibroblast growth factor 21, or FGF21 ... in behavioral motivation and brain reward signaling," which was published in the January ...

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...

Ovarian cancer (OC), the most lethal gynecological malignancy, is the fifth leading cause of cancer-related death in women. Despite advances in treatment, the primary challenges in overcoming ovarian ...