Pegcetacoplan inhibits C3 activation by binding to C3 and its activation fragment C3b, thereby reducing C3 glomerular fragment deposition in patients with C3G and primary IC-MPGN.

C3 glomerulopathy (C3G) and immune-complex membranoproliferative glomerulonephritis (IC-MPGN) are two diseases that have a ...

When you think of hematuria, you think of a state in which your urine is mixed with red blood. However, the presence of ...

Glomerulonephritis refers to acute and chronic kidney diseases caused by injury to the glomerulus, a part of the kidney responsible for filtering blood. If the kidney is injured, it is unable to ...

February 8, 2023 A glomerulus (kidney filter) from a patient with diabetes. The diabetic patient has no visible glycocalyx within the blood vessels. [University of Bristol] ...

Glomerulonephritis may be acute or chronic. All forms can be progressive, meaning that without treatment, it can lead to further kidney damage. Acute glomerulonephritis may be primary or secondary ...

For example, Antarctic fishes do not have glomeruli in their kidneys, which are a cluster of capillaries at the end of a kidney tubule that help filter waste products from the blood.

Chronic kidney disease (CKD). After you've lived with IgA nephropathy for a while, your kidneys may be too damaged to filter wastes and fluid out of your blood.

Li PK, Garcia-Garcia G, Lui SF, et al. Kidney health for everyone everywhere - from prevention to detection and equitable access to care. Clin Nephrol. 2020;93 (3):111-122. doi: 10.5414 ...