A new study published in Nature Structural & Molecular Biology reveals how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that ...

For all species, the process of DNA replication requires the use of multiple different DNA polymerase enzymes. The primary function of these unique multisubunit enzymes is to ensure optimal DNA ...

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, ...

DURHAM, N.C. -- Biochemists have performed detailed structural studies that reveal for the first time how an enzyme key to DNA replication stalls when an error occurs ...

The National Cancer Institute has awarded USC scientists $3.5 million for a study of the enzyme that faithfully copies our genetic information, enabling it to pass from one generation to the next. The ...

Failures in DNA replication can lead to cancer, birth defects or other harm Video shows single pieces of double-helix DNA being copied Single-molecule view gives new insights into this process ...

A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19. The discovery could lead to the ...

Promega files patent for first-of-its-kind enzyme that minimizes stutter artifacts in STR analysis Reduced stutter polymerase enhances accuracy, efficiency and reliability of DNA profiling in forensic ...

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications. Now, a new ...

There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...

We have previously reported [Ohno, T., Sweet, R. W., Hu, R., DeJak, D. & Spiegelman, S. (1977) Proc. Natl. Acad. Sci. USA 74, 764-768] on the purification and ...