Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues ...

Scientists use pore-forming toxin to punch holes in the membrane of HIV virus-like particles, making the capsid accessible to external cell factors and small molecules.

A new image reveals the precise structure of the protective protein coat, or "capsid," shared by hundreds of known viruses. The image, which appears this week in the Proceedings of the National ...

A new paper published this week in the journal Nature describes how researchers pieced together the entire molecular structure of the protein shell of the HIV virus using GPU-based simulations.

Many pathogenic viruses require a specific structure to be infectious, and their proteins form that structure in vivo with remarkable fidelity. The same proteins, ... Electron microscopy images of ...

Caption: Structure of a HIV capsid (Left) Central slice view of a HIV virus-like particle with pore-forming toxin on the membrane (Middle) Atomic model of a HIV capsid (Right) Density map of HIV ...

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.