Double-strand breaks are among the most difficult forms of DNA damage for cells to repair because they disrupt the continuity of DNA and leave no intact template to base new strands on ... my team and ...

What made ribose the sugar of choice for life's code? Scientists at Scripps Research may have cracked a major part of this ...

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...

RNA is also made of a long string of bases: guanine, cytosine and adenine (like DNA), but instead of thymine it has uracil — which is what turned up in the sample from Ryugu.

RNA's other bases were not found in the sample, though Oba believes they could be present at levels too low to be detected with the method used to find uracil.

Scientists have used an optical trap to track the movement of RNA polymerase (RNAP), showing that the enzyme appears to shift along DNA one base pair at a time. Although many experts had expected this ...

In addition to the Watson-Crick base pairing usually seen between complementary nucleic acid strands, Nielsen found that PNAs could bind to the outside of double-stranded RNA or DNA by forming ...