"Now that we know how Aplp1 and Lag3 interact, we have a new way of understanding how alpha-synuclein contributes to the disease progression of Parkinson's disease," neuroscientist Xiaobo Mao from ...

A major research breakthrough on Parkinson's disease revealed that an already FDA-approved cancer drug could help stem the ...

Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the ...

Genetic studies have strongly established a prominent role of α-synuclein (α- syn) missense and multiplication mutations in causing Parkinson's disease (PD). In neurons, α-syn is almost ...

"We will continue our close collaboration with the Parkinson's community as we further evaluate the data to determine next steps." Alpha-synuclein is a protein that tends to get misfolded and ...

Over time, the disease can also affect memory and lead to dementia. A similar condition called Lewy Body Dementia (LBD), ...

The assay for a particular abnormal form of the protein alpha-synuclein – known as αSyn-SAA – could also be used to diagnose people with Parkinson’s more quickly, help identify the best ...

Now, a new study from Renmin Hospital of Wuhan University provides strong evidence that kidney failure may also contribute to the development of Parkinson’s disease by triggering the spread of ...

Inhibikase Therapeutics announced disappointing results from a Phase 2 trial for its Parkinson’s disease drug, risvodetinib, ...

New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other ...

eight Parkinson’s patients and two suffering from Lewy body dementia. Images of the subjects’ brains captured with PET showed patients had a larger volume of alpha-synuclein than their healthy ...