Potosi is a village in Grant County, Wisconsin, United States. The population was 646 at the 2020 census. The village is in the Town of Potosi. Potosi is located where Wisconsin's lead ore belt intersects with the Mississippi. The post office was originally located between Van Buren and Head of the Hollow, then at Van Buren, then at La Fayette. In 18…Potosi is a village in Grant County, Wisconsin, United States. The population was 646 at the 2020 census. The village is in the Town of Potosi. Potosi is located where Wisconsin's lead ore belt intersects with the Mississippi. The post office was originally located between Van Buren and Head of the Hollow, then at Van Buren, then at La Fayette. In 1839, the leaders of three settlements decided to combine the villages. The new, larger community was named Potosi, and the post office moved one last time, to the center of the new, merged community.
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